Amoxicillin/Clavulanate
Amoxicillin is a bacteriocidal drug which prevents bacterial cell wall synthesis. Active against a wide range of bacteria. The beta-lactamase inhibitor clavulanate increases the spectrum of bacteria affected by blocking bacterial enzyme breakdown of the amoxicillin.
Used against a wide range of bacterial infections. Note that some bacteria may be resistant such as Pseudomonas.
Nausea and diarrhoea are the commonest adverse reactions.
Methimazole
Interferes with the synthesis of thyroid hormones
Control of thyroid hormone levels in cats with hyperthyroidism.
Vomiting and inappetence which is often transient. Itchiness. Rare effects on liver and blood cells.
Benazepril
Inhibits conversion of angiotensin I to angiotensin II. This causes dilation of blood vessels reducing the resistance against which the heart has to pump. Also results in reduced salt and water retention reducing blood volume and pressure. Reduces glomerular pressure in the kidney. Raised glomerular pressure is thought to have a role in the progression of kidney failure and renal protein loss.
Reduce backward regurgitaion of blood in hearts with valvular damage by reducing resistance to forward motion. See canine heart disease. Treatment of hypertension. Slowing progression of renal disease especially in cats with chronic renal failure. Reducing protein loss in protein losing nephropathy.
Weakness due to hypotension usually in combination with other drugs. Reduced kidney function usually in combination with other drugs. Anorexia, vomiting and diarrhoea are rare.
Prednisolone
Anti-inflammatory, immunosuppressive and antifibrotic
Management of allergies such as atopy. Control of immune mediated conditions such as immune mediated anaemia or thrombocytopenia. Management of inflammatory conditions such as inflammatory bowel disease. Management of certain cancers such as lymphoma or mast cell tumours.
Increased appetite and thirst. Muscle loss and thinning of skin with long term use. Stomach ulceration especially if used with Non-Steroidal Anti-Inflammatory Drugs (NSAIDs). Worsening of diabetic conditions. Suppression and atrophy of the adrenal glands with long term use.
Meloxicam
Non-Steroidal Anti-Inflammatory Drug (NSAID). Inhibits COX-2 enzyme thereby limitng the production of prostaglandins involved in inflammation
Control of acute and chronic pain including arthritis and perioperative pain.
Diarrhoea and vomiting. Stop drug if persists for more than 1 day and seek advice. Vomiting of blood or the passing of black stools (melena) is indicative of gastrointestinal ulceration. Stop medication and seek immediate veterinary advise.
Carprofen
Non-Steroidal Anti-Inflammatory Drug (NSAID). Inhibits COX-2 enzyme thereby limitng the production of prostaglandins involved in inflammation
Control of acute and chronic pain including arthritis and perioperative pain.
Diarrhoea and vomiting. Stop drug if persists for more than 1 day and seek advice. Vomiting of blood or the passing of black stools (melena) is indicative of gastrointestinal ulceration. Stop medication and seek immediate veterinary advise.
Pimobendan
Increases the strength of heart contraction. Dilation of blood vessels reducing the resistance against which the heart has to pump.
Reduce backward regurgitaion of blood in hearts with valvular damage by reducing resistance to forward motion. See canine heart disease. Increase force of cardiac contraction in dogs with valvular heart disease or dilated cardiomyopathy.
Vomiting may occur.
Trilostane
Blocks synthesis of glucocorticoid and mineralcorticoid steroids.
Treatment of Cushings syndrome. Doseage is to effect. Steroid levels need to measured 10 days after starting medication and 4-6 hours after dosing using an ACTH stimulation test protocol. Doseage is adjusted as a result of test results. Further testing is performed until control appears stable.
Depression, weakness and anorexia due to overdoseage.
Propentofylline
Xanthine derivitive that increases blood flow to heart, muscle and brain. Also has a bronchodilatory effect.
Treatment of age related behavioural problems such as canine cognitive dysfunction ("senility").
No information available.
Carbimazole
Drug is metabolized to methimazole which interferes with the production of thyroid hormones.
Control of thyroid hormone levels in cats with hyperthyroidism. Once daily dosing.
Vomiting and inappetence which is often transient. Itchiness. Rare effects on liver and blood cells.
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